Crisfield is a city in Somerset County, Maryland, United States, located on the Tangier Sound, an arm of the Chesapeake Bay. The population was 2,723 at the 2000 census. It is included in the Salisbury, Maryland Metropolitan Statistical Area. Crisfield has the distinction of being the southernmost incorporated city in Maryland. The city now known as Crisfield began as Annemessex Neck, a small fishing village.