Huntington, is a city in Cabell and Wayne counties in the U.S. state of West Virginia, along the Ohio River. Most of the city is in Cabell County, for which it is the county seat. A small portion of the city, mainly the neighborhood of Westmoreland, is in Wayne County. Its population was 49,138 at the 2010 census. Huntington is a part of the Huntington-Ashland, WV-KY-OH, Metropolitan Statistical Area (MSA). As of 2009, the MSA's population was 285,624.